DETECTion of PAH in SSc

The PAH risk calculator is a tool for all physicians managing patients with systemic sclerosis (SSc). The calculator was developed and validated in the DETECT study, which was designed and carried out by a group of SSc and PAH experts1 and was supported by Actelion Pharmaceuticals Ltd.

The calculator was developed for daily clinical practice. It will help to screen SSc patients for pulmonary arterial hypertension (PAH), which is a serious condition that develops in 8-12% of SSc patients and is one of the leading causes of death in patients with SSc2. The calculator is based on an algorithm with a high sensitivity and specificity and can help to decide which SSc patients should be evaluated using echocardiography, and of those, patients who should be referred for right heart catheterisation that may provide definite PAH diagnosis.

Date of preparation for this mobile application: May 2022, EMEA CP-316836

References

Coghlan JG et al. Ann Rheum Dis 2014; 73(7):1340–1349.

Kolstad KD et al. Chest 2018; 154(4):862–871.

CP-308328

DOP: April 2022

Disclaimer: The objective of this PAH risk calculator is to provide an evidence based screening tool for PAH in SSc patients. The PAH risk calculator may not be used to make a diagnosis of PAH and does not replace specialist PAH clinical judgement. This PAH risk calculator has been developed based on the DETECT Study. This PAH risk calculator is intended for use only by healthcare professionals. It is recommended to use the PAH risk calculator in centres specialized in the management of SSc, and/or centres that work closely with these specialized SSc centres.

Janssen Pharmaceutica NV takes no responsibilities for death, injury or worsening of health as a direct result of any information inputted into this calculator. No data is saved within the app. Please ensure that you are only using the latest version of this app.